KinTek Explorer Version 3.0™
This page contains a brief description of the new features in the ground breaking software KinTek Explorer™ version 3.0. To fully experience the power of KinTek Explorer™, Download the software now!, and Purchase a Professional License.
Multithreading: A major re-programming effort has enabled use of multiple computer cores, which increases speed approximately 6-fold on a Mac 8-core computer. Performance improvements are somewhat less under Windows due to inefficiencies beyond our control. You will see that multiple FitSpace calculations are now done simultaneously using different computer cores to greatly accelerate these time consuming calculations.
Mac OSX and Windows Native File Directories: Saving and opening files are now performed using the file directory forms native to Windows and Mac OSX. This makes finding and opening files easier by using familiar search functions.
One-dimensional FitSpace: As a simplified version of FitSpace™, we now offer a 1 dimensional search. Each parameter is varied and the best fit is obtained by allowing all other constants to vary. The change in chi2 can be used to obtain reliable error estimates for each parameter.
Manual Entry of FitSpace Boundaries: The boundaries over which the program will search for changes in chi2 as a function of each parameter can be entered manually. This is especially useful in preparing a publication quality figure.
Graph Zoom: Left-click and drag on the graph to define a box to zoom in. Use right-click-drag to pan the view window area. Use Ctrl-W to return to the full graph display.
Simultaneous fitting of multiple time resolved spectra: We have improved the simultaneous fitting of multiple time-resolved spectra by solving equations to get a single set of extinction coefficients that best accounts for all spectra. This can be very useful since spectra collected different concentrations of reactants can contribute differently to the accuracy of determining spectra and rate constants governing individual species.
Global Fit Weight: We added a new feature to alter the weight given to different experiments during data fitting. Under the Experiment Editor, you can change the Global Fit Weight for a given experiment to any positive number.
Display of Residuals: For each experiment, the residuals (yobserved-ycalculated) can be displayed as an aid to evaluating goodness of fit.
Modeling Pulse-Chase Experiments: Pulse-chase experiments can be modeled using the > symbol.
Modeling Equilibrium Titrations: Equilibrium titration experiments can now be modeled using the @ symbol. Complex reactions can now be modeled precisely without the inaccurate simplifying assumptions required to solve equations describing multiple equilibria.